How HIV Affects the Immune System

By Nucleus Medical Media

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MEDICAL ANIMATION TRANSCRIPT: HIV, or human immunodeficiency virus, is the retrovirus that eventually causes AIDS or acquired immunodeficiency syndrome. Over time, HIV infection suppresses the immune response, resulting in a spectrum of diseases leading to AIDS. HIV is transmitted from an infected person via specific bodily fluids, including blood, semen, vaginal fluids, and breast milk. White blood cells or leukocytes defend the body from infection. One group of leukocytes called T lymphocytes or T cells is part of a direct immune response against infected cells and tumor cells. During HIV infection, HIV targets and kills certain cells in the immune system. HIV attacks CD4 T cells, which are a sub-type of T cells that signal other leukocytes to attack a specific pathogen. HIV replicates inside the CD4 T cells, which not only kills them but also allows the virus to spread and infect healthy cells. As HIV continues to replicate and destroy more CD4 T cells, the body becomes defenseles

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